BocNH-PEG12-CH2CH2NH2 manufacturers
- NHBoc-PEG12-amine
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- $0.00 / 1g
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2024-03-25
- CAS:1642551-09-4
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | BocNH-PEG12-CH2CH2NH2 Basic information |
| Product Name: | BocNH-PEG12-CH2CH2NH2 | | Synonyms: | BocNH-PEG12-CH2CH2NH2;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azatetracontanoic acid, 40-amino-, 1,1-dimethylethyl ester;NHBoc-PEG12-amine;Boc-N-amido-PEG12-amine;inhibit,Inhibitor,PROTAC Linkers,Boc-NH-PEG-12-NH2,Boc NH PEG12 NH2,BocNHPEG12NH2;BocNH-PEG12-CH2CH2NH2/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azatetracontanoic acid, 40-amino-, 1,1-dimethylethyl ester;tert-Butyl (38-amino-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontyl)carbamate;Boc-NH-PEG12-amine | | CAS: | 1642551-09-4 | | MF: | C31H64N2O14 | | MW: | 688.84 | | EINECS: | | | Product Categories: | | | Mol File: | 1642551-09-4.mol |  |
| | BocNH-PEG12-CH2CH2NH2 Chemical Properties |
| Boiling point | 695.1±55.0 °C(Predicted) | | density | 1.088±0.06 g/cm3(Predicted) | | pka | 12.23±0.46(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | BocNH-PEG12-CH2CH2NH2 Usage And Synthesis |
| Biological Activity | Boc-NH-PEG12-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | BocNH-PEG12-CH2CH2NH2 Preparation Products And Raw materials |
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