| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-HNF1B
Purity:Prestige Antibody pow Package:100μL Remarks:HPA002083
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| | ANTI-HNF-1 Basic information |
| Product Name: | ANTI-HNF-1 | | Synonyms: | Anti-HNF1B antibody produced in rabbit;Anti-HNF2;Anti-LFB3;Anti-HGNC:11630;ANTI-HNF-1;Anti-ADMCKD2;Anti-HNFJ;Anti-MCKD2 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HNF-1 Structure]() |
| | ANTI-HNF-1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-HNF-1 Usage And Synthesis |
| Uses | These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | HNF1B (hepatocyte nuclear factor 1 β), a homeodomain, is an atypical POU (Pit-1, Oct-1, andUnc-86) transcription factor which is associated with the early vertebrate development and embryonic survival. It is expressed in the pancreas, kidney, lung, ovary, testis, and throughout the gastrointestinal tract. | | Biochem/physiol Actions | The expression of HNF1B (hepatocyte nuclear factor 1 β) is upregulated in papillary renal cell tumours (RCTs) as well as in some conventional RCCs, renal oncocytomas, chromophobe RCCs and normal kidneys. On the other hand, its expression is suppressed in Wilms′tumours. It is a nuclear protein required for liver-specific expression. It can binds to the promoters and enhancers of a variety of genes expressed in liver along with the proximal element (PE) of the albumin gene. |
| | ANTI-HNF-1 Preparation Products And Raw materials |
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