| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-Heat Shock Protein 70 antibody produced in mouse
Purity:clone BRM-22, ascites fluid Package:100UL Remarks:H5147-100UL
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| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Recombinant Human HSPA8 Protein, His Tag
Purity:>90% as determined by SDS-PAGE Package:50μg, 100μg
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| Company Name: |
Shanghai Huzhen Industrial Co., LTD
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| Tel: |
021-60345367 13916550749 |
| Email: |
sales@shzbio.com |
| Products Intro: |
Product Name:Hsc70
Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1880;200ul/RMB 2900 Remarks:2410008N15Rik; Constitutive heat shock protein 70; Heat shock 70 kDa protein 8; Heat shock 70kD protein 10; Heat shock 70kD protein 8; Heat shock 70kDa protein 8; Heat shock cognat
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| | ANTI-HEAT SHOCK PROTEIN 70 Basic information |
| | ANTI-HEAT SHOCK PROTEIN 70 Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-HEAT SHOCK PROTEIN 70 Usage And Synthesis |
| Uses | The antibody titer of at least 1:5,000 was determined by immunoblotting using bovine brain extract. | | General Description | Monoclonal Anti-Heat Shock Protein 70 (mouse IgG1 isotype) is derived from the BRM-22 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified bovine brain HSP70. Heat shock protein family A (Hsp70) member 1A (HSPA1A), is encoded by the gene mapped to human chromosome 6p21.33. It is widely expressed in all tissues. The encoded protein is characterized with an N-terminal ATPase domain of 45 kDa and a C-terminal substrate binding domain of 25 kDa. | | Biochem/physiol Actions | Members of the HSP70 family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes. In addition, several possible roles have been attributed to the HSP70 family of proteins, in the immune response. It has been shown that alcoholic liver disease is associated with intracytoplasmic accumulation of HSP70. HSP72 was found to increase dramatically in the brains of Alzheimer′s disease patient, and was localized exclusively in neuritic plaques and neurofibrillary tangles. HSP70 concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed. |
| | ANTI-HEAT SHOCK PROTEIN 70 Preparation Products And Raw materials |
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