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(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid

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(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Suppliers list
Company Name: Jinan Carbotang Biotech Co.,Ltd.
Tel: +8615866703830
Email: figo.gao@foxmail.com
Products Intro: Product Name:(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
CAS:159858-33-0
Purity:98% Package:5KG;1KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Val-Cit
CAS:159858-33-0
Purity:98.00% Package:1 mg；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203
Email: info@chemextension.com
Products Intro: Product Name:Val-Cit
CAS:159858-33-0
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
Tel: +86-15680926068 +86-15680926068
Email: 1924344760@confluore.cn
Products Intro: Product Name:Val-Cit
CAS:159858-33-0
Purity:>95.00% Package:1g
Company Name: Shanghai Send Pharmaceutical Technology Co., Ltd.  
Tel: 021-58088081 Q1224289022
Email: danping@shsendpharm.com
Products Intro: Product Name:(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
CAS:159858-33-0
Purity:98% Package:1kg;2kg;3kg

(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid manufacturers

  • Val-Cit
  • Val-Cit pictures
  • $0.00 / 1g
  • 2024-03-29
  • CAS:159858-33-0
  • Min. Order: 1g
  • Purity: >95.00%
  • Supply Ability: 1g
(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Basic information
Product Name:(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
Synonyms:(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid;Val-Cit;Val-Cit-OH;ValCit,ADC Linkers,Val Cit,Antibody-drug conjugates linkers,Inhibitor,inhibit,Val-Cit;L-Ornithine, L-valyl-N5-(aminocarbonyl)-
CAS:159858-33-0
MF:C11H22N4O4
MW:274.32
EINECS:
Product Categories:Linker;ADC LINKER
Mol File:159858-33-0.mol
(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Structure
(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Chemical Properties
Boiling point 554.0±50.0 °C(Predicted)
density 1.218±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DCM, DMF
pka3.13±0.10(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Usage And Synthesis
DescriptionVal-Cit is a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.
Biological ActivityVal-Cit is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs).
in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Preparation Products And Raw materials
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