| Company Name: |
BOC Sciences
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16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:FTBMT
CAS:1358575-02-6
Purity:98% by HPLC Package:1G;10G;100G Remarks:FTBMT is a novel and selective GPR52 agonist (EC50 = 75 nM, Emax = 122%). FTBMT displays antipsychotic and procognitive properties without causing catalepsy in rodents.
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| Product Name: | FTBMT | | Synonyms: | FTBMT;Benzamide, 4-[3-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methyl-;FTBMT >=98% (HPLC);4-(3-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-5
-methyl-1H-1,2,4-triazol-1-yl)-2-methylbenzamide;inhibit,FTBMT,Inhibitor;TP-024;4-(3-(3-Fluoro-5-(trifluoromethyl)benzyl)-5-methyl-1H-1,2,4-triazol-1-yl)-2-methylbenzamide;FTBMT, 10 mM in DMSO | | CAS: | 1358575-02-6 | | MF: | C19H16F4N4O | | MW: | 392.35 | | EINECS: | | | Product Categories: | | | Mol File: | 1358575-02-6.mol |  |
| | FTBMT Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO:69.62(Max Conc. mg/mL);177.44(Max Conc. mM) | | form | Solid | | color | Light yellow to orange |
| | FTBMT Usage And Synthesis |
| Uses | FTBMT is a GPR52 receptor agonist with an EC50 value of 71 nM. Studies demonstrate antipsychotic-like effects of FTBMT in murine models of schizophrenia. FTBMT elicits beneficial effects on cognitive processes such as spatial working memory and long-term memory in mice. | | Biological Activity | FTBMT is an orally available, selective and potent agonist of GPR52. It exhibits antipsychotic and procognitive properties without causing catalepsy in rodents. FTBMT improves recognition memory in a novel object recognition test and mitigates MK-801-induced working memory deficits in a radial arm maze test in rats. | | storage | Store at -20°C |
| | FTBMT Preparation Products And Raw materials |
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