| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:SLP7111228 (hydrochloride)
CAS:1449768-48-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:SLP7111228 hydrochloride
CAS:1449768-48-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:SLP7111228 (hydrochloride)
CAS:1449768-48-2
|
|
| | SLP7111228 (hydrochloride) Basic information |
| | SLP7111228 (hydrochloride) Chemical Properties |
| solubility | DMF: 12.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml | | form | A crystalline solid |
| | SLP7111228 (hydrochloride) Usage And Synthesis |
| Description | SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively. It induces a concentration-dependent decrease in sphingosine-1-phosphate (S1P; ) in U937 cells but has no effect on sphingosine levels. In vivo, SLP7111228 decreases blood levels of S1P in a dose-dependent manner in rats. |
| | SLP7111228 (hydrochloride) Preparation Products And Raw materials |
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