Company Name: |
ShangHai Biochempartner Co.,Ltd
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Tel: |
177-54423994 17754423994 |
Email: |
2853530910@QQ.com |
Products Intro: |
Product Name:CYM-5478 CAS:870762-83-7 Purity:98% HPLC LCMS Package:5mg;50mg
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CYM-5478 manufacturers
- CYM-5478
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- $233.00 / 1mg
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2024-10-24
- CAS:870762-83-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| CYM-5478 Basic information |
Product Name: | CYM-5478 | Synonyms: | CYM-5478;2(1H)-Pyridinone, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-;1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone;1-[2-(1-benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)-1,2-dihydropyridin-2-one | CAS: | 870762-83-7 | MF: | C21H19F3N2O2 | MW: | 388.38 | EINECS: | | Product Categories: | | Mol File: | 870762-83-7.mol | |
| CYM-5478 Chemical Properties |
Boiling point | 527.1±50.0 °C(Predicted) | density | 1.23±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO: soluble | form | A crystalline solid | pka | -2.22±0.70(Predicted) | color | White to off-white |
| CYM-5478 Usage And Synthesis |
Description | CYM 5478 is a sphingosine-1-phosphate receptor 2 (S1P2) agonist (EC50 = 0.78 μM in a reporter assay). It is selective for S1P2 over S1P1 and S1P3-5 in a TGFα-shedding assay (EC50s = 119, 1,690, 1,950, >10,000, and >10,000 nM, respectively). CYM 5478 (0.1-10 μM) reduces serum starvation-induced decreases in C6 rat glioma cell viability. It also reduces accumulation of reactive oxygen species (ROS) and apoptosis induced by cisplatin in C6 cells when used at a concentration of 10 μM. |
| CYM-5478 Preparation Products And Raw materials |
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