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Product Name:4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride
CAS:446031-79-4
Purity:98% Package:50MG;100MG,1G,5G,100G
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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:SSR 180711 hydrochloride
CAS:446031-79-4
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
BOC Sciences
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Product Name:SSR 180711 hydrochloride
CAS:446031-79-4
Purity:≥98% by HPLC Remarks:SSR 180711 hydrochloride is a partial agonist at α7 nAChR. It enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. SSR 180711 leads to an increase of extracel
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4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride manufacturers
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| | 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride Basic information |
| | 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride Usage And Synthesis |
| Uses | SSR 180711 Hydrochloride is a partial agonist at α7 nAChR. It enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. It increases extracellular dopamine levels in rat prefrontal cortex and also exhibits antidepressant-like properties. | | in vivo | SSR180711 hydrochloride rapidly penetrates into the brain (ID50=8?mg/kg; p.o.). SSR180711 hydrochloride dose-dependently inhibits the specific [3H]α-BTX binding in the mouse brain (ID50=8.3 and 7.5?mg/kg for p.o. and i.p., respectively)[1].
SSR180711 hydrochloride (1-10?mg/kg for i.p.; 10-30 mg/kg for p.o.) dose-dependently increases extracellular acetylcholine (ACh) levels in the hippocampus and prefrontal cortex of freely moving rats[1].
SSR180711 hydrochloride (0.1, 0.3, 1?mg/kg; i.v.) dose-dependently increases firing rate[1].
| | storage | Store at -20°C |
| | 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride Preparation Products And Raw materials |
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