N2-iso-Butyroyl-3'-O-methylguanosine

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CAS:160107-07-3
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CAS:160107-07-3
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CAS:160107-07-3
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N2-iso-Butyroyl-3'-O-methylguanosine Basic information
Product Name:N2-iso-Butyroyl-3'-O-methylguanosine
Synonyms:N2-iso-Butyroyl-3'-O-methylguanosine;Guanosine, 3'-O-methyl-N-(2-methyl-1-oxopropyl)- (9CI);N2-Isobutyryl-3'-OMe-guanosine;N2-iso-Butyroyl-3’-O-methylguanosine
CAS:160107-07-3
MF:C15H21N5O6
MW:367.36
EINECS:
Product Categories:Modified(deoxy)nucleoside
Mol File:160107-07-3.mol
N2-iso-Butyroyl-3'-O-methylguanosine Structure
N2-iso-Butyroyl-3'-O-methylguanosine Chemical Properties
density 1.68±0.1 g/cm3(Predicted)
pka9.16±0.20(Predicted)
Safety Information
MSDS Information
N2-iso-Butyroyl-3'-O-methylguanosine Usage And Synthesis
UsesN2-iso-Butyroyl-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
References[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
N2-iso-Butyroyl-3'-O-methylguanosine Preparation Products And Raw materials
Tag:N2-iso-Butyroyl-3'-O-methylguanosine(160107-07-3) Related Product Information
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