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| 4,4,4-TRIFLUORO-1-(2-FURYL)-1,3-BUTANEDIONE Basic information |
| 4,4,4-TRIFLUORO-1-(2-FURYL)-1,3-BUTANEDIONE Chemical Properties |
Melting point | 19-21 °C(lit.) | Boiling point | 203 °C(lit.) | density | 1.391 g/mL at 25 °C(lit.) | refractive index | n20/D 1.528(lit.) | Fp | 189 °F | storage temp. | 2-8°C | pka | 5.56±0.23(Predicted) | form | powder to lump to clear liquid | color | White or Colorless to Yellow to Orange | FreezingPoint | 20.0 to 22.0 ℃ | BRN | 168085 | InChIKey | OWLPCALGCHDBCN-UHFFFAOYSA-N | CAS DataBase Reference | 326-90-9(CAS DataBase Reference) | EPA Substance Registry System | 1,3-Butanedione, 4,4,4-trifluoro-1-(2-furanyl)- (326-90-9) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36/37/39 | WGK Germany | 3 | TSCA | Yes | HazardClass | IRRITANT | HS Code | 29321900 |
| 4,4,4-TRIFLUORO-1-(2-FURYL)-1,3-BUTANEDIONE Usage And Synthesis |
Chemical Properties | clear yellow liquid | Uses | 4,4,4-Trifluoro-1-(2-furyl)-1,3-butanedione (tfa) may be used in the following studies:
- As capping ligand in the synthesis of [Eu(tfa)3]2bpm complexes (bpm=2,2′-bipyrimidine).
- As reagent in the multistep synthesis of [13CD2]benzylamine.
- As reagent in the synthesis of 3-trifluoromethyl-2-arylcarbonylquinoxaline 1,4-di-N-oxide derivatives by reacting with corresponding benzofurazan oxides.
- In the efficient syntheses of perfluoroalkyl substituted azoles.
- Synthesis of 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives.
| General Description | 4,4,4-Trifluoro-1-(2-furyl)-1,3-butanedione (furoyltrifluoroacetone, FTFA) is a β-diketone. Its cytotoxic activity against human cultured tumor and normal cells has been evaluated. Reports suggest that 4,4,4-trifluoro-1-(2-furyl)-1,3-butanedione partially inhibits the oxidation of ferrocyanide in ETP (electron transport particles) isolated from beef heart mitochondria. Its reaction with N,N,N′,N′-tetramethylalkyl diamines to form ionic adducts has been investigated. The conformational analysis of the enol and keto form of FTFA has been reported. |
| 4,4,4-TRIFLUORO-1-(2-FURYL)-1,3-BUTANEDIONE Preparation Products And Raw materials |
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