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2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D

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Company Name: Aladdin Scientific
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Products Intro: Product Name:2-((3-Trifluoromethyl)phenyl)histamine dimaleate
CAS:162049-83-4
Purity:>=98% Package:$94.9/5mg;Bulk package Remarks:98%
Company Name: Sigma-Aldrich  
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Products Intro: Product Name:2-((3-Trifluoromethyl)phenyl)histamine dimaleate
CAS:162049-83-4
Purity:>=98% (HPLC), powder Package:5MG Remarks:T4951-5MG
Company Name: Energy Chemical  
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Products Intro: Product Name:2-((3-Trifluoromethyl)phenyl)histamine dimaleate >=98% (HPLC), powder
CAS:162049-83-4
Purity:98% (HPLC), powder Package:5mg Remarks:NULL
Company Name: Riedel-de Haen AG  
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Products Intro: Product Name:2-((3-Trifluoromethyl)phenyl)histamine dimaleate
CAS:162049-83-4
Company Name: Guangzhou WeiBo Chemical Co., Ltd.  
Tel: 020-36393398
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2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Basic information
Product Name:2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D
Synonyms:2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D;2-((3-Trifluoromethyl)phenyl)histamine dimaleate >=98% (HPLC), powder
CAS:162049-83-4
MF:C12H12F3N3.2C4H4O4
MW:487.38
EINECS:
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Mol File:162049-83-4.mol
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Structure
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Chemical Properties
storage temp. 2-8°C
solubility H2O: ~20 mg/mL
form solid
color off-white
Safety Information
Hazard Codes T
Risk Statements 25-37/38-41
Safety Statements 26-39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
MSDS Information
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Usage And Synthesis
Uses2-((3-Trifluoromethyl)phenyl)histamine dimaleate has been used to study the induction of goblet cell secretion in rats3. 2-((3-Trifluoromethyl)phenyl)histamine dimaleate has also been used to study the role of H1 receptor in COX-2 regulation and prostanoid homeostasis in human vascular endothelial cells4.
Biochem/physiol Actions2-((3-Trifluoromethyl)phenyl)histamine dimaleate was found to be the most potent and selective H1 histamine receptor agonist of a panel of compounds in functional in vitro studies on histamine H2, H3, and other neurotransmitter receptors. It showed better potency at the guinea pig H1 histamine receptor than at the human H1 histamine receptor (pKi : 5.9). The selectivity of 2-((3-Trifluoromethyl)phenyl)histamine dimaleate was found to be 2138 (H1:H2), > 64 (H1:H3), 1000 (H1:M3), 105 (H1: a1), 708 (H1:β1), and 71 (H1:5HT2A). 2-((3-Trifluoromethyl)phenyl)histamine dimaleate does not cross the blood-brain barrier.
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Preparation Products And Raw materials
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