| Company Name: |
Chengdu Peter-like Biotechnology Co., Ltd.
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| Tel: |
028-81700200 18108052721 |
| Email: |
2850505130@qq.com |
| Products Intro: |
Product Name:JAK3 covalent inhibitor-1
CAS:2300106-50-5
Purity:>=98% Package:5mg;10mg;20mg;50mg;100mg;200mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:JAK3 covalent inhibitor-1;JAK3 covalent inhibitor1,JAK3 covalent inhibitor 1,JAK-3 covalent inhibitor-1
CAS:2300106-50-5
Purity:98% Package:5 mg
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| | JAK3 covalent inhibitor-1 Basic information |
| Product Name: | JAK3 covalent inhibitor-1 | | Synonyms: | JAK3 COVALENT INHIBITOR-1;JAK3 covalent inhibitor1,JAK3 covalent inhibitor 1,JAK-3 covalent inhibitor-1;Benzenesulfonamide, N-[(1R,3S)-3-(cyanoamino)-2,3-dihydro-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-inden-1-yl]-3-fluoro- | | CAS: | 2300106-50-5 | | MF: | C22H17FN6O2S | | MW: | 448.47 | | EINECS: | | | Product Categories: | | | Mol File: | 2300106-50-5.mol |  |
| | JAK3 covalent inhibitor-1 Chemical Properties |
| density | 1.55±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.70±0.40(Predicted) |
| | JAK3 covalent inhibitor-1 Usage And Synthesis |
| Description | JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1].
JAK3|11 nM (IC50)
| | References | [1]. Casimiro-Garcia A, et al. Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J Med Chem. 2018 Dec 13;61(23):10665-10699. |
| | JAK3 covalent inhibitor-1 Preparation Products And Raw materials |
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