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CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem

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Products Intro: CAS:473728-67-5
CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem Basic information
Product Name:CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem
Synonyms:CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem;CXCR2 antagonist, Cpd 19 - CAS 473728-67-5;Benzamide, 3-[[2-(cyclopentylamino)-3,4-dioxo-1-cyclobuten-1-yl]amino]-2-hydroxy-N-methyl-
CAS:473728-67-5
MF:C17H19N3O4
MW:329.35
EINECS:
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Mol File:473728-67-5.mol
CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem Structure
CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem Chemical Properties
density 1.39±0.1 g/cm3(Predicted)
pka8.04±0.50(Predicted)
Safety Information
MSDS Information
CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem Usage And Synthesis
General DescriptionA cell-permeable, cyclobutenedione derivative that acts as a potent antagonist of chemokine receptor CXCR2 (IL8RB) (IC50 = 8 nM). Reported to inhibit CXCR2-mediated chemotaxis in a CXCR2 expressing cell line (IC50 = 145 nM). Exhibits good stability in human and rat liver microsomal preparations (>50% remaining after 30 min at 37°C).
CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem Preparation Products And Raw materials
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