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H3-K56ac

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Company Name: Hefei KS-V Peptide Biotechnology Co., Ltd.  
Tel: 0551-65120828 17368858770
Email: sales1@difficultpeptide.com
Products Intro: Product Name:H3-K56ac
Purity:≥95%,1mg/5mg/10mg Package:1g/;1mg/
H3-K56ac Basic information
Uses
Product Name:H3-K56ac
Synonyms:H3-K56ac
CAS:
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MW:0
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Mol File:Mol File
H3-K56ac Structure
H3-K56ac Chemical Properties
Safety Information
MSDS Information
H3-K56ac Usage And Synthesis
UsesH3K56ac is the synthesized histone H3 peptide corresponding to residues within 1-135 of human histone H3 with acetylation K56 modification. H3K56ac is a covalent modification known as a mark of newly replicated chromatin as well as replication-independent histone replacement. H3K56ac is important for chromatin remodeling and serves as a marker of new nucleosomes during DNA replication but its role in the cell cycle is debated. Lysine 56 is located at the amino-terminal αN-helix and close to the site where the DNA enters and exits the nucleosome. Due to its location on the lateral surface of the nucleosome, which is close to the DNA entry/exit site and interacts with DNA. The studies on yeast might not apply to the mammals. Mammalian cells do not express HATs with high specificity to K56. Sirtuins can catalyze the removal of the acetyl group from K56. H3K56ac levels are elevated in cancer and pluripotent cells. TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage.
H3-K56ac Preparation Products And Raw materials
Tag:H3-K56ac Related Product Information
H3S10ph H3R42me2a H3-K27me1 H3-K56ac-K122Ub H3-K36me1 H3-K4me2 H3K64ac H3-K36me3 H3-K9me3 H3-K27me3 H3-K9me1 H3K18ac H3-K36me2 H3K79me2 H3-K4me1 H3-K27me2 H3-K9me2 H3K4Me3