| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-HDAC3
Purity:Prestige Antibodies P Package:0.2mL Remarks:HPA052052
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| | ANTI-HDAC3 Basic information |
| | ANTI-HDAC3 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-HDAC3 Usage And Synthesis |
| Uses | Anti-Histone Deacetylase 3 (HDAC3) antibody produced in rabbit has been used in:
- immunohistochemistry
- western blotting
- immunoprecipitation
| | General Description | Histone deacetylase 3 (HDAC3) is an epigenetic modifier and is expressed in various tissues. It belongs to the class I subfamily of histone deacetylases. The HDAC3 gene is mapped on to human chromosome 5q31.3. | | Biochem/physiol Actions | Histone acetylation is a dynamic process whose levels are determined by the net activities of HATs and the competing enzymes histone deacetylases (HDACs). Both activities are associated with the nuclear matrix. Six or seven different mammalian HDACs have been described. HDAC1, HDAC2 and HDAC3 are similar to yeast Rpd3 protein, while HDAC4, HDAC5 and HDAC6 are similar to yeast Hda1 protein. Histone deacetylases activities were often, but not always, associated with transcriptional repression and nucleosomal condensations. HDAC1, HDAC2 and several other HDACs are the catalytic subunits of different multiprotein regulatory complexes. |
| | ANTI-HDAC3 Preparation Products And Raw materials |
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