ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN

ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Suppliers list
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:Monoclonal Anti-hnRNP-A2/B1
Purity:monoclonal DP3B3, purified from hybridoma cell culture Package:200μL Remarks:R4653
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Email:
Products Intro: Purity:IgG fraction of antiserum, lyophilized powder Remarks:clone 18E4, purified immunoglobulin, buffered aqueous solution
Company Name: SIGMA-RBI  
Tel: 800 736 3690 (Orders)
Email:
Products Intro:
Company Name: Novus Biologicals, Inc.  
Tel: 888 506 6887
Email: novus@novusbio.com
Products Intro:
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Basic information
Product Name:ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN
Synonyms:MONOCLONAL ANTI-HNRNP-A2/B1;MONOCLONAL ANTI-HNRNP-L;MONOCLONAL ANTI-HNRNP M1-M4;MONOCLONAL ANTI-HNRNP-Q;ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN;ANTI-HNRNP M1-M4;Anti-heterogeneous nuclear ribonucleoprotein M1-M4;Monoclonal Anti-hnRNP M1-M4 antibody produced in mouse
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MW:0
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Mol File:Mol File
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Structure
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Chemical Properties
storage temp. -20°C
form buffered aqueous suspension
Safety Information
Hazard Codes Xn
Risk Statements 21/22
Safety Statements 36/37
WGK Germany -
MSDS Information
ProviderLanguage
SigmaAldrich English
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Usage And Synthesis
UsesMonoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
  • enzyme linked immunosorbent assay (ELISA)
  • immunoblotting
  • immunoprecipitation
  • immunocytochemistry

General DescriptionThis gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. (provided by RefSeq)
Biochem/physiol ActionsIn cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats).
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Preparation Products And Raw materials
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