Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Monoclonal Anti-hnRNP-A2/B1 Purity:monoclonal DP3B3, purified from hybridoma cell culture Package:200μL Remarks:R4653
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Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
Email: |
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Products Intro: |
Purity:IgG fraction of antiserum, lyophilized powder Remarks:clone 18E4, purified immunoglobulin, buffered aqueous solution
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Company Name: |
SIGMA-RBI
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Tel: |
800 736 3690 (Orders) |
Email: |
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Products Intro: |
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| ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Basic information |
Product Name: | ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN | Synonyms: | MONOCLONAL ANTI-HNRNP-A2/B1;MONOCLONAL ANTI-HNRNP-L;MONOCLONAL ANTI-HNRNP M1-M4;MONOCLONAL ANTI-HNRNP-Q;ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN;ANTI-HNRNP M1-M4;Anti-heterogeneous nuclear ribonucleoprotein M1-M4;Monoclonal Anti-hnRNP M1-M4 antibody produced in mouse | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | ![ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Structure]() |
| ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Chemical Properties |
storage temp. | -20°C | form | buffered aqueous suspension |
Hazard Codes | Xn | Risk Statements | 21/22 | Safety Statements | 36/37 | WGK Germany | - |
| ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Usage And Synthesis |
Uses | Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
- enzyme linked immunosorbent assay (ELISA)
- immunoblotting
- immunoprecipitation
- immunocytochemistry
| General Description | This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. (provided by RefSeq) | Biochem/physiol Actions | In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats). |
| ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Preparation Products And Raw materials |
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