| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:BACE-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Shanghai Huzhen Industrial Co., LTD
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| Tel: |
021-60345367 13916550749 |
| Email: |
sales@shzbio.com |
| Products Intro: |
Product Name:BACE1
Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1880;200ul/RMB 2900 Remarks:APP beta secretase; Asp 2; ASP2; Aspartyl protease 2; BACE 1; BACE; Beta secretase 1; Beta secretase; Beta site amyloid beta A4 precursor protein cleaving enzyme; Beta site amyloid
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| Company Name: |
AntibodySystem
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| Tel: |
18162686757 18162686757 |
| Email: |
info@biolabreagent.com |
| Products Intro: |
Product Name:BACE1
CAS:158736-49-3
Purity:95% SDS-PAGE Package:1mg;100ug
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| Product Name: | BACE-1 | | Synonyms: | MEMAPSIN-2;HUMAN BETA-SECRETASE;HUMAN BACE-1;ASP-2;B-SECRETASE;BETA-SECRETASE ENZYME;BETA-SECRETASE HUMAN;BACE-1 | | CAS: | 158736-49-3 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![BACE-1 Structure]() |
| | BACE-1 Chemical Properties |
| storage temp. | 2-8°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | - |
| | BACE-1 Usage And Synthesis |
| Uses | Human β-secretase or BACE1 has been used to study the binding reaction between amyloid precursor protein and β-secretase. It has also been used in BACE1 assay. | | Biochem/physiol Actions | BACE1 (β-site APP-cleaving enzyme 1) is a transmembrane aspartyl protease responsible for cleaving the amyloid precursor protein (APP). BACE1-mediated cleavage of amyloid precursor protein (APP) is the first step during the generation of pathogenic amyloid-β peptides, hence making it the major drug target for Alzheimer′s disease (AD). Increased levels of enzymatic activity of BACE1 was found in cerebrospinal fluid from patients having both mild cognitive impairment (MCI) and AD, thereby suggesting the importance of BACE1 enzymatic activity in conversion of MCI to AD. |
| | BACE-1 Preparation Products And Raw materials |
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