3-(Trifluoromethyl)benzaldehyde

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Products Intro: Product Name:3-(Trifluoromethyl)benzaldehyde
CAS:454-89-7
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Products Intro: Product Name:3-(Trifluoromethyl)benzaldehyde
CAS:454-89-7
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CAS:454-89-7
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CAS:454-89-7
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Products Intro: Product Name:3-(Trifluoromethyl)benzaldehyde
CAS:454-89-7
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3-(Trifluoromethyl)benzaldehyde Basic information
Uses
Product Name:3-(Trifluoromethyl)benzaldehyde
Synonyms:m-Trifluoromethoxy benzaldehyde;3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-3-tolualdehyde;Alpha-Trifluoro-M-tolualdehyde;3-(TrifluoroMethyl)benzaldehyde, 97% 25GR;3-(TrifluoroMethyl)benzaldehyde, 97% 5GR;3-Formylbenzotrifluoride, alpha,alpha,alpha-Trifluoro-m-tolualdehyde;3-(three fluoroMethyl)benzeneforMaldehyde;Between the three groups in benzene forMaldehyde
CAS:454-89-7
MF:C8H5F3O
MW:174.12
EINECS:207-228-1
Product Categories:Benzotrifluoride Series;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;3-(Trifluoromethyl)benzaldehyde;bc0001
Mol File:454-89-7.mol
3-(Trifluoromethyl)benzaldehyde Structure
3-(Trifluoromethyl)benzaldehyde Chemical Properties
Boiling point 83-86 °C30 mm Hg(lit.)
density 1.301 g/mL at 25 °C(lit.)
refractive index n20/D 1.465(lit.)
Fp 155 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
color Clear colorless to very slightly orange
Specific Gravity1.301
Sensitive Air Sensitive
BRN 2327537
InChIKeyNMTUHPSKJJYGML-UHFFFAOYSA-N
CAS DataBase Reference454-89-7(CAS DataBase Reference)
NIST Chemistry ReferenceBenzaldehyde, 3-(trifluoromethyl)-(454-89-7)
EPA Substance Registry SystemBenzaldehyde, 3-(trifluoromethyl)- (454-89-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR UN3082 - class 9 - PG 3 - DOT NA1993 - Environmentally hazardous substances, liquid, n.o.s. HI: all (not BR)
WGK Germany 3
10-23
TSCA T
HazardClass IRRITANT
HS Code 29130000
MSDS Information
ProviderLanguage
alpha,alpha,alpha-Trifluoro-3-tolualdehyde English
SigmaAldrich English
ACROS English
ALFA English
3-(Trifluoromethyl)benzaldehyde Usage And Synthesis
Uses3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.
Chemical PropertiesCLEAR COLOURLESS TO VERY SLIGHTLY ORANGE LIQUID
Uses3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-╬│-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.
Synthesis Reference(s)Journal of the American Chemical Society, 68, p. 426, 1946 DOI: 10.1021/ja01207a024
General DescriptionAldol reaction of 3-(trifluoromethyl)benzaldehyde with hydroxyacetone in the aldolase antibody 38C2-ionic liquid system has been investigated.
Tag:3-(Trifluoromethyl)benzaldehyde(454-89-7) Related Product Information
2-Methylbenzotrifluoride Benzaldehyde 3-Aminobenzotrifluoride 2-(Trifluoromethyl)benzoic acid (Trifluoromethyl)trimethylsilane 3-(Trifluoromethyl)anisole 3-(Trifluoromethyl)benzoyl chloride 3-Trifluoromethylphenol 3-(Trifluoromethyl)phenylacetone 3-(Trifluoromethyl)benzoic acid Trifluoromethanesulfonic acid p-Tolualdehyde 4-(Trifluoromethoxy)benzaldehyde 4-(Trifluoromethyl)benzoic acid alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID 1-NAPHTHALEN-2-YL-ETHYLAMINE 3-(3-METHYLPHENYL)PROPIONIC ACID