ML218 hydrochloride

ML218 hydrochloride Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:ML218 hydrochloride
CAS:2319922-08-0
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:ML 218 hydrochloride
CAS:2319922-08-0
Purity:>=99%(HPLC) Package:$215.9/10mg;$904.9/50mg;Bulk package Remarks:99%(HPLC)
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:ML218 hydrochloride;ML218 hydrochloride,ML-218 hydrochloride
CAS:2319922-08-0
Purity:98% Package:5 mg
Company Name: Shanghai Tachizaki Biomedical Research Center  
Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Products Intro: Product Name:ML218 hydrochloride
CAS:2319922-08-0
Purity:98%+ HPLC Package:10mg,500mg,1g,2g,5g
ML218 hydrochloride Basic information
Product Name:ML218 hydrochloride
Synonyms:ML218 hydrochloride,ML-218 hydrochloride
CAS:2319922-08-0
MF:C19H27Cl3N2O
MW:405.79
EINECS:
Product Categories:
Mol File:2319922-08-0.mol
ML218 hydrochloride Structure
ML218 hydrochloride Chemical Properties
solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
Safety Information
MSDS Information
ML218 hydrochloride Usage And Synthesis
Biological ActivityML 218 hydrochloride is a selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in an in vivo rat model of Parkinson's disease. Displays no significant inhibition of L- or N-type calcium channels, Kir6 (KATP) or KV11.1 (hERG) potassium channels. ML 218 hydrochloride inhibits oral cancer cell proliferation. Orally active.
storageStore at +4°C
ML218 hydrochloride Preparation Products And Raw materials
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