| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:ROR agonist-1;ROR agonist1,ROR agonist 1
CAS:2361528-74-5
Purity:98% Package:5 mg
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| | ROR agonist-1 Basic information |
| Product Name: | ROR agonist-1 | | Synonyms: | ROR agonist-1;ROR agonist1,ROR agonist 1;Benzeneacetamide, α-(acetylamino)-4-(ethylsulfonyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, (αR)- | | CAS: | 2361528-74-5 | | MF: | C21H20F6N2O5S | | MW: | 526.45 | | EINECS: | | | Product Categories: | | | Mol File: | 2361528-74-5.mol |  |
| | ROR agonist-1 Chemical Properties |
| Boiling point | 743.4±60.0 °C(Predicted) | | density | 1.455±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.24±0.15(Predicted) |
| | ROR agonist-1 Usage And Synthesis |
| Description | ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5[1].
pIC 50: 7.5 (human primary TH 17 cells)[1] | | References | [1]. von Berg S, et al. Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2. ACS Med Chem Lett. 2019 May 29;10(6):972-977. |
| | ROR agonist-1 Preparation Products And Raw materials |
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