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3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel-

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3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel- Suppliers list
Company Name: ChemStrong Scientific Co.,Ltd  
Tel: 0755-0755-66853366 13670046396
Email: sales@chem-strong.com
Products Intro: Product Name:Fosaprepitant Impurity 11
CAS:2206135-44-4
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: 18616537568
Email: hanfangpharma@126.com
Products Intro: CAS:2206135-44-4
Purity:98%+ Package:1g；5g；10g；100g; 1kg
3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel- Basic information
Product Name:3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel-
Synonyms:3-Des-(4-fluorophenyl) 3-(2R,3S,R)-(4-Fluorobiphen-3-yl) Aprepitant;3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel-
CAS:2206135-44-4
MF:C29H25F7N4O3
MW:610.52
EINECS:
Product Categories:
Mol File:2206135-44-4.mol
3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel- Structure
3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel- Chemical Properties
density 1.44±0.1 g/cm3(Predicted)
pka8.05±0.20(Predicted)
Safety Information
MSDS Information
3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel- Usage And Synthesis
Uses3-Des-(4-fluorophenyl) 3-(2R,3S,R)-(4-Fluorobiphen-3-yl) Aprepitant is a derivative of Aprepitant (A729800), which is a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel- Preparation Products And Raw materials
Tag:3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro[1,1'-biphenyl]-3-yl)-4-morpholinyl]methyl]-1,2-dihydro-, rel-(2206135-44-4) Related Product Information