Company Name: |
Changzhou Hopschain Chemical Co.,Ltd.
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Tel: |
0519-85528066 13775048983 |
Email: |
sales@hopschem.com |
Products Intro: |
Product Name:SH-5 CAS:701976-54-7 Purity:98% Package:1mg;10mg;100mg;1g
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Product Name: | SH-5 | Synonyms: | SH-5;AKT INHIBITOR II;D-3-DEOXY-2-O-METHYL-MYO-INOSITOL 1-[(R)-2-METHOXY-3-(OCTADECYLOXY)PROPYL HYDROGEN PHOSPHATE];PIA 5;1-Deoxy-6-O-methyl-L-chiro-inositol 5-[(2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate];L-chiro-Inositol, 1-deoxy-6-O-methyl-, 5-[(2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate];SH5 PIA5. LchiroInositol 1deoxy6Omethyl 5(2R)2methoxy3(octadecyloxy)propyl hydrogen phosphate. Akt inhibitor II | CAS: | 701976-54-7 | MF: | C29H59O10P | MW: | 598.75 | EINECS: | | Product Categories: | SiChem | Mol File: | 701976-54-7.mol | ![SH-5 Structure](CAS/20200611/GIF/701976-54-7.gif) |
Enzyme inhibitor | This phosphatidylinositol analogue (FWfree-acid = 598.76 g/mol), also known as SH-5, inhibits the proto-oncogenic serine/threonine kinase Akt (protein kinase B), inducing apoptosis. Specific inhibition of Akt by these compounds validates ligand design targeted to the PH domains of crucial signaling proteins, thus providing a unique class of possible cancer therapeutics. |
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