Company Name: |
Nanjing XiZe Biotechnology CO., Ltd.
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Tel: |
025-66023220 0086-15250997978 |
Email: |
1511893459@qq.com |
Products Intro: |
Product Name:Apixaban Impurity 265 CAS:1589504-29-9 Purity:95% HPLC Package:10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Apixaban Impurity 102 Basic information |
Product Name: | Apixaban Impurity 102 | Synonyms: | Apixaban Impurity 102;2(1H)-Pyridinone, 3-chloro-5,6-dihydro-1-[4-(2-oxo-1-piperidinyl)phenyl]-;Apixaban Impurity 265 | CAS: | 1589504-29-9 | MF: | C16H17ClN2O2 | MW: | 304.77 | EINECS: | | Product Categories: | | Mol File: | 1589504-29-9.mol |  |
| Apixaban Impurity 102 Chemical Properties |
Boiling point | 545.5±50.0 °C(Predicted) | density | 1.33±0.1 g/cm3(Predicted) | pka | 1.05±0.20(Predicted) |
| Apixaban Impurity 102 Usage And Synthesis |
Uses | 3-Chloro-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydropyridin-2(1H)-one is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. 3-Chloro-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydropyridin-2(1H)-one is prepared in a multi-step synthesis with the advantages of being low cost, simple, and with large yields and high purity. |
| Apixaban Impurity 102 Preparation Products And Raw materials |
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