Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:(S)-Aspartimide CAS:73537-92-5 Purity:>95% Remarks:(S)-Aspartimide is a bioactive byproduct formed during solid-phase peptide synthesis (SPPS) of aspar
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:(S)-Aspartimide CAS:73537-92-5 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| 2,5-Pyrrolidinedione, 3-amino-, (3S)- Basic information |
Product Name: | 2,5-Pyrrolidinedione, 3-amino-, (3S)- | Synonyms: | 2,5-Pyrrolidinedione, 3-amino-, (3S)-;(S)-Aspartimide;(S)-3-Aminopyrrolidine-2,5-dione;2,5-Pyrrolidinedione, 3-amino-, (S)- | CAS: | 73537-92-5 | MF: | C4H6N2O2 | MW: | 114.1 | EINECS: | | Product Categories: | | Mol File: | 73537-92-5.mol | ![2,5-Pyrrolidinedione, 3-amino-, (3S)- Structure](CAS/20210111/GIF/73537-92-5.gif) |
| 2,5-Pyrrolidinedione, 3-amino-, (3S)- Chemical Properties |
Boiling point | 337.0±35.0 °C(Predicted) | density | 1.337±0.06 g/cm3(Predicted) | solubility | DMSO: soluble; Methanol: soluble | form | A solid | pka | 8.93±0.50(Predicted) |
| 2,5-Pyrrolidinedione, 3-amino-, (3S)- Usage And Synthesis |
Description | (S)-Aspartimide is a byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides.1 Aspartimide is formed by cyclization of aspartic acid during Fmoc removal or peptide coupling.2 | References | 1. Ruczyński, J., Lewandowska, B., Mucha, P., et al. Problem of aspartimide formation in Fmoc-based solid-phase peptide synthesis using Dmab group to protect side chain of aspartic acid J. Pept. Sci. 14(3),335-341(2008). 2. Neumann, K., Farnung, J., Baldauf, S., et al. Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups Nat. Commun. 11(1),982(2020). |
| 2,5-Pyrrolidinedione, 3-amino-, (3S)- Preparation Products And Raw materials |
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