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2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-

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2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:Complement factor D-IN-2
CAS:1903742-34-6
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Complement factor D-IN-2
CAS:1903742-34-6
Purity:99.51% Package:1mg;113USD|2mg;163USD|5mg;268USD
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Products Intro: Product Name:Complement factor D-IN-2
CAS:1903742-34-6
Package:1 mg；10 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
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Products Intro: Product Name:ComplementfactorD-IN-2
CAS:1903742-34-6
Purity:99% Package:$338.9/1mg;$710.9/5mg;$1120.9/10mg;Bulk package Remarks:99%
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
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Products Intro: Product Name:Complement factor D-IN-2
CAS:1903742-34-6
Purity:0.98 Package:10G:100G

2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- manufacturers
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- Basic information
Product Name:2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-
Synonyms:2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-;Complement factor D-IN-2;JYN42346;Complement System,complement,diseases,inhibit,factor,Complement factor D IN 2,autoimmune,Inhibitor,Complement factor DIN2;(1R,3S,5R)-2-{2-[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-2-azabicyclo[3.1.0]hexane-3-carboxamide
CAS:1903742-34-6
MF:C27H24BrN7O3
MW:574.43
EINECS:
Product Categories:
Mol File:1903742-34-6.mol
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- Structure
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- Chemical Properties
Boiling point 849.1±65.0 °C(Predicted)
density 1.67±0.1 g/cm3(Predicted)
pka11.72±0.20(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- Usage And Synthesis
Biological ActivityComplement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases[1]. Complement factor D-IN-2 reduces the excessive activation of complement factor D[1].
References[1]. GADHACHANDA VR, et, al. Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders. WO2015130838A1.
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- Preparation Products And Raw materials
Tag:2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-(1903742-34-6) Related Product Information