| Company Name: |
Chemsky（shanghai）International Co.,Ltd.
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:Oxprenolol
CAS:1189649-47-5
Purity:98% Package:2300RMB/1Mg; 14000RMB/10Mg
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| Company Name: |
Artis Biotech Co. Ltd.
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| Tel: |
19138486554 18582380095 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Oxprenolol-d7 HCl
CAS:1189649-47-5
Purity:98% Package:1g m;5g m;10g m
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| Company Name: |
Jinan ponder chemical co. LTD
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| Tel: |
0531-0000 |
| Email: |
thinklifescience@163.com |
| Products Intro: |
Product Name:1189649-47-5
CAS:1189649-47-5
Purity:99% HPLC Package:1KG;500G;100G；50G;1G
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| | OXPRENOLOL Basic information |
| Product Name: | OXPRENOLOL | | Synonyms: | 2-PROPANOL,1-(2-ALLYLOXYPHENOXY)-3-(ISOPROPYLAMINO)-;OXPRENOLOL;1-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol:hydrochloride;1-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol;[2H7]-Oxprenolol Hydrochloride;Oxprenolol-d7 HCl | | CAS: | 1189649-47-5 | | MF: | C15H23NO3 | | MW: | 265.34802 | | EINECS: | | | Product Categories: | Amines;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals | | Mol File: | Mol File |  |
| | OXPRENOLOL Chemical Properties |
| Melting point | 97-98°C | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | Dichloromethane (Slightly), Methanol (Slightly) | | form | Solid | | pka | pKa 9.5 (Uncertain) | | color | White to Off-White |
| | OXPRENOLOL Usage And Synthesis |
| Chemical Properties | White Solid | | Originator | Trasicor,Ciba Geigy ,Italy,1970 | | Uses | Oxprenolol is a free base of Oxprenolol Hydrochloride(O870500) which is a β-Adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic. | | Manufacturing Process | 75 grams of pyrocatechol monoallyl ether, 75 grams of epichlorohydrin, 75 grams of potassium carbonate and 400 ml of acetone are stirred and heated at the boil for 12 hours. The potassium carbonate is then filtered off. The solvent is distilled off in a water-jet vacuum. The residual oil is dissolved in ether and agitated with 2 N sodium hydroxide solution. The ether is separated, dried and distilled off. The residue is distilled in a water-jet vacuum. 3-(ortho-allyloxy-phenoxy)-1,2-epoxypropane passes over at 145° to 157°C under 11 mm Hg pressure. A solution of 15 grams of 3-(ortho-allyloxyphenoxy)-1,2-epoxypropane and 15 grams of isopropylamine in 20 ml of ethanol is refluxed for 4 hours. The excess amine and the alcohol are then distilled off under vacuum, to leave 1-isopropylamino-2-hydroxy-3-(orthoallyloxy-phenoxy)-propane which melts at 75° to 80°C after recrystallization from hexane. | | Therapeutic Function | Antiarrhythmic |
| | OXPRENOLOL Preparation Products And Raw materials |
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