伊维菌素B1B
中文名称 | 伊维菌素B1B |
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中文同义词 | 伊维菌素B1B;伊维菌素杂质2;依维菌素B1B;伊维菌素H2B1B |
英文名称 | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- |
英文同义词 | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-;avermectin H2B1b;Component B1b;22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a;22,23-Dihydroavermectin B1b;Dihydroavermectin B1b;5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a |
CAS号 | 70209-81-3 |
分子式 | C47H72O14 |
分子量 | 861.07 |
EINECS号 | 274-384-5 |
相关类别 | 微生物代谢物 |
Mol文件 | 70209-81-3.mol |
结构式 |
伊维菌素B1B 性质
沸点 | 934.1±65.0 °C(Predicted) |
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密度 | 1.24±0.1 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | DMF:可溶; DMSO:可溶;乙醇:可溶;甲醇:可溶 |
形态 | 固体 |
酸度系数(pKa) | 12.42±0.70(Predicted) |
稳定性 | 对温度敏感 |
Ivermectin and Ivermectin B1b are the most potent inhibitors of contraction and motility in both susceptible isolates (
H. contortus
McMaster and and
O. circumcincta
McMaster) also show the highest resistance ratios in both species.
Vermectin is a macrocyclic lactone that acts as a positive allosteric modulator of α7 nicotinic acetylcholine receptors (nAChRs) but has no modulatory activity on 5-HT3 receptors.
Ivermectin B1b causes snail death.
安全信息
危险品运输编号 | 2588 |
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危险等级 | 6.1(a) |
包装类别 | II |
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/04/30 | HY-125729 | 伊维菌素B1B Ivermectin B1b | 70209-81-3 | 500μg | 6570元 |