Log in | Join Free | china | japan | germany

Isosorbide dinitrate U.S.P24,BP98

Request For Quotation
Isosorbide dinitrate U.S.P24,BP98 Suppliers list
Company Name: A.T.CHEMICAL   
Tel: 0755-86655561 81899190
Email: Jeffreyxu@atchem.net
Products Intro:
Isosorbide dinitrate U.S.P24,BP98 Basic information
Product Name:Isosorbide dinitrate U.S.P24,BP98
Synonyms:Isosorbide dinitrate U.S.P24,BP98;Diluted isosorbide dinitrate
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Isosorbide dinitrate U.S.P24,BP98 Structure
Isosorbide dinitrate U.S.P24,BP98 Chemical Properties
Safety Information
MSDS Information
Isosorbide dinitrate U.S.P24,BP98 Usage And Synthesis
General DescriptionIsosorbide dinitrate,1,4:3,6-dianhydro-D-glucitol dinitrate (Isordil, Sorbitrate),occurs as a white, crystalline powder. Its watersolubility is about 1 mg/mL.
Isosorbide dinitrate, as a sublingual or chewable tablet,is effective in the treatment or prophylaxis of acute anginalattacks. When it is given sublingually, the effect begins inabout 2 minutes, with a shorter duration of action thanwhen it is given orally. Oral tablets are not effective inacute anginal episodes; the onset of action ranges from 15to 30 minutes. The major route of metabolism involves denitrationto isosorbide 5-mononitrate. This metabolite has amuch longer half-life than the parent isosorbide dinitrate.As such, this particular metabolite is marketed in a tabletform that has excellent bioavailability with much less firstpassmetabolism than isosorbide dinitrate. Isosorbide ismarketed as a combination therapy with hydralazine underthe tradename BiDil specifically for African Americanswith CHF.
Isosorbide dinitrate U.S.P24,BP98 Preparation Products And Raw materials
Tag:Isosorbide dinitrate U.S.P24,BP98 Related Product Information
Isosorbide dinitrate Isosorbide