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R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE

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R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Suppliers list
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:R(+)-SKF-81297 hydrobromide
CAS:253446-15-0
Purity:>=98% Package:$491.9/5mg;Bulk package Remarks:98%
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:R(+)-SKF-81297
CAS:253446-15-0
Purity:>= 98 % HPLC, solid Package:5mg Remarks:S179
Company Name: Shanghai Anhua Biotechnology Co., Ltd.  
Tel: 021-61263375 18168859245
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Products Intro: Product Name:(R)-(+)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CAS:253446-15-0
Purity:95%;98%;99% Package:0.1g;0.5g;1g;5g;25g;100g;1kg;5kg
Company Name: Wuxi maimo topp biotechnology co., LTD  
Tel: 13771048682
Email: alice@mimotopes.cn
Products Intro: Product Name:(R)-(+)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CAS:253446-15-0
Purity:95%;98%;99% Package:0.1g;0.5g;1g;5g;25g;100g;1kg;5kg
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
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Products Intro: Product Name:R(+)-SKF-81297 hydrobromide
CAS:253446-15-0
R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Basic information
Product Name:R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE
Synonyms:R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE;R(+)-SKF-81297;(5R)-9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
CAS:253446-15-0
MF:C16H16ClNO2.BrH
MW:370.672
EINECS:
Product Categories:
Mol File:253446-15-0.mol
R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Structure
R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Chemical Properties
solubility H2O: soluble6mg/mL
form solid
color white to off-white
optical activity[α]22/D +15.14°, c = 0.52 in DMF(lit.)
Safety Information
WGK Germany 3
MSDS Information
R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Usage And Synthesis
UsesR(+)-SKF-81297 Hydrobromide is a dopamine D1 agonist.
UsesR(+)-SKF-81297 hydrobromide has used as D1-type dopamine receptor agonist:
  • to test it effect on the spike firing in rat retinal ganglion cells
  • in human embryonic kidney (HEK) 293T cells
  • to test its inhibitory effect in microglial cells

Biochem/physiol ActionsSKF-81297 administration in spontaneously hypertensive rats (SHR) induces an increase in expression of proto-oncogene c-fos mRNA leading to biphasic effect on locomotion. It favors the turnover of phosphoinositide and adenylyl cyclase. SKF-81297 is involved in the stimulation of neurons, in particular the postsynaptic striatal neurons.
R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Preparation Products And Raw materials
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