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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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| Products Intro: |
Product Name:N-(2-AMinoethyl)-5-chloroisoquinoline-8-sulfonaMide Dihydrochloride
CAS:1177141-67-1
Package:100Mg,10Mg,5Mg
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| | N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Basic information |
| Product Name: | N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride | | Synonyms: | CKI-7 Dihydrochloride;N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride;CKI-7 dihydrochlorid;N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride;CKI-7 2HCL;Serum and glucocorticoid-regulated kinase,inhibit,nestin,S6K,Inhibitor,CK1,Casein Kinase,Ribosomal S6 Kinase (RSK),differentiation,SGK,CKI-7,Cyclin dependent kinase,neural,Serum-glucocorticoid regulated kinase,S6K1,MSK1,CDK,CKI 7,Wnt,CKI7,βIII-tubulin,Sox1;CKI-7 (hydrochloride) | | CAS: | 1177141-67-1 | | MF: | C11H14Cl3N3O2S | | MW: | 358.67176 | | EINECS: | | | Product Categories: | Inhibitors;Protein Kinase Inhibitors and Activators;All Inhibitors | | Mol File: | 1177141-67-1.mol |  |
| | N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Chemical Properties |
| Melting point | 187-189°C | | storage temp. | -20°C | | solubility | H2O: >5mg/mL | | form | solid | | color | white to light tan |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 |
| | N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Usage And Synthesis |
| Chemical Properties | Beige Solid | | Uses | Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases | | Biochem/physiol Actions | CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM. | | storage | Store at -20°C |
| | N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Preparation Products And Raw materials |
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