PROTAC EGFR degrader 2

PROTAC EGFR degrader 2 Suppliers list

Company Name:	Wuhan Yuxiang Medical Technology Co., Ltd.
Tel:	13971275651
Email:	sales@whyxpharma.com
Products Intro:	Product Name:PROTAC EGFR degrader 2 CAS:3031336-58-7 Purity:95% HPLC Package:1g;5g;10g

PROTAC EGFR degrader 2 Basic information

PROTAC EGFR degrader 2 Chemical Properties

density	1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	12.00±0.43(predicted)
form	Solid
color	Light yellow to yellow

Safety Information

MSDS Information

PROTAC EGFR degrader 2 Usage And Synthesis

Uses	PROTAC EGFR degrader 2 is a potent PROTAC EGFR degrader. PROTAC EGFR degrader 2 exhibits excellent antiproliferative activity with IC50 of 4.0 nM and good EGFR degradation activity with DC50 of 36.51 nM. PROTAC EGFR degrader 2 can be used for the synthesis of nitroreductase (NTR)-responsive PROTAC[1].
IC 50	EGFR: 36.51 nM (DC₅₀)
References	[1] Shi S, et al. Rational Design for Nitroreductase (NTR)-Responsive Proteolysis Targeting Chimeras (PROTACs) Selectively Targeting Tumor Tissues. J Med Chem. 2022;65(6):5057-5071. DOI:10.1021/acs.jmedchem.1c02221

PROTAC EGFR degrader 2 Preparation Products And Raw materials

Tag:PROTAC EGFR degrader 2(3031336-58-7) Related Product Information

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