| Company Name: |
CNS Labs Private Limited
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| Tel: |
+91-9963542411 +91-8284987467 |
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info@cnslabs.in |
| Products Intro: |
Product Name:(R)5-(2-Benzenesulfonyl-vinyl)-3-(1-methyl-pyrrolidin-2-ylmethyl)-1H-indole
CAS:180637-89-2
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:R-5-(2-Benzenesulphonylethenyl)-3-(N-Methylpyrrolidin-2-ylMethyl)-1H-indole
CAS:180637-89-2
Package:50Mg,5Mg
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| | 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Basic information |
| | 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Chemical Properties |
| Boiling point | 617.7±55.0 °C(Predicted) | | density | 1.263 | | solubility | soluble in Dichloromethane, Dimethylformamide, Methanol | | pka | 16.92±0.30(Predicted) |
| | 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Usage And Synthesis |
| Chemical Properties | Red Solid | | Uses | (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is the free base of (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Hydrobromide (B120725), which is an impurity of Eletriptan (E505000). Eletriptan is a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines (1,2,3). (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is also an intermediate in the synthesis of 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-1-[1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indol-5-yl]-2-(phenylsulfonyl)ethyl]-5-[(1E)-2-(phenylsulfonyl)ethenyl]-1H-indole (M320195). |
| | 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE Preparation Products And Raw materials |
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