甲苯咔啉
| 中文名称 | 甲苯咔啉 |
|---|---|
| 中文同义词 | 甲苯咔啉 |
| 英文名称 | 5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE |
| 英文同义词 | 5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE;MEBHYDROLIN;2,3,4,5-Tetrahydro-2-methyl-5-(phenylmethyl)-1H-pyrido[4,3-b]indole;2,3,4,5-Tetrahydro-2-methyl-5-phenylmethyl-1H-pyrido[4,3-b]indole;N-Methyl-9-benzyltetrahydro-γ-carboline;1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2-methyl-5-(phenylmethyl)-;3-Benzyl-6-methyl-1,2,3,4-tetrahydro-gamma-carboline;5-Benzyl-1,3,4,5-tetrahydro-2-methyl-2H-pyrido[4,3-b]indole |
| CAS号 | 524-81-2 |
| 分子式 | C19H20N2 |
| 分子量 | 276.38 |
| EINECS号 | 208-364-4 |
| 相关类别 | Intermediates of Sertraline |
| Mol文件 | 524-81-2.mol |
| 结构式 |  |
甲苯咔啉 性质
| 熔点 | 95° |
|---|---|
| 沸点 | bp1 207-215° |
| 密度 | 1.0246 (rough estimate) |
| 折射率 | 1.5640 (estimate) |
| 储存条件 | Store at -20°C |
| 溶解度 | 二甲基亚砜：83.33 mg/mL（301.51 mM） |
| 形态 | 固体 |
| 酸度系数(pKa) | pKa 2.55 ± 0.18;7.63± 0.04(H2O,t undefined,I=0.30(NaCl)) (Uncertain) |
| 颜色 | 白色至米白色 |
Mebhydrolin 是一种特异性组胺 H1 受体拮抗剂。
Histamine H1-receptor
Mebhydrolin is a specific histamine H 1 -receptor antagonist with minimal sedative properties and comparing it with the effects of chlorpromazine, the archetypical phenothiazine. Mebhydrolin exerts an antihistaminic effect over the period of the ethanol interaction study.