| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:JC-1.Iodide
CAS:47729-63-5
Purity:>98% Package:5mg
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| Company Name: |
Synchem OHG
|
| Tel: |
+49 5662 408730 |
| Email: |
info@synchem.de |
| Products Intro: |
Product Name:JC-1;CBIC2(3)
5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide
CAS:47729-63-5
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
CAS:47729-63-5
|
JC-1 manufacturers
- JC-1
-
- $0.00 / 25mg
-
2024-03-29
- CAS:47729-63-5
- Min. Order: 25mg
- Purity: >99.00%
- Supply Ability: 25mg
|
| Product Name: | JC-1 | | Synonyms: | BENZIMIDAZOLOCARBOCYANINE IODIDE, 5,5',6,6'-TETRACHLORO-1,1',3,3'-TETRAETHYL-;BIS(5,6-DICHLORO-1,3-DIETHYL-2-BENZIMIDAZOLE)TRIMETHINECYANINE IODIDE;IMIDACARBOCYANINE IODIDE, 1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLORO-;CBIC2;CBIC2(3);D 383;D 383 (DYE);NK 1420 | | CAS: | 47729-63-5 | | MF: | C25H27Cl4IN4 | | MW: | 652.22 | | EINECS: | | | Product Categories: | | | Mol File: | 47729-63-5.mol |  |
| storage temp. | -20C | | form | solid |
| Uses | JC-1 is commonly used to determine mitochondrial membrane potential. It is a cationic carbocyanine dye that is membrane permeable and is often used for flow cytometry and fluorescent microscopy. This dye changes color as the membrane potential increases. At higher potentials, JC-1 forms aggregates, which changes the fluorescence emission color from green to red. Dyes and metabolites. | | Definition | ChEBI: 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide is a cyanine dye and an organic iodide salt. It has a role as a fluorochrome. It contains a 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine. | | General Description | A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential ΔΨm in cells, tissues, and isolated mitochondria. It labels mitochondria with high membrane potential orange and mitochondria with low membrane potential green. Mitochondrial depolarization is indicated by a decrease in the red/green fluorescence intensity ratio. Ideal for detection of collapse of ΔΨm induced by uncouplers of mitochondrial respiration. The potential-sensitive color shift is due to concentration-dependent formation of red fluorescent J-aggregates. JC-1 has also been used in a functional assay of multidrug-resistance cells and in apoptosis-related mitochondrial modifications. | | Biochem/physiol Actions | Product does not compete with ATP. | | storage | -20°C |
| | JC-1 Preparation Products And Raw materials |
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