1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol

1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol Basic information
Product Name:1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol
Synonyms:1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol;Lophocerine
CAS:19485-63-3
MF:C15H23NO2
MW:249.35
EINECS:
Product Categories:
Mol File:19485-63-3.mol
1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol Structure
1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol Chemical Properties
Boiling point 358.3±42.0 °C(Predicted)
density 1.035±0.06 g/cm3(Predicted)
pka10.25±0.40(Predicted)
Safety Information
MSDS Information
1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol Usage And Synthesis
DescriptionThis alkaloid belongs to the isoquinoline group and is one of the cactus bases being found in Lophocereus schottii. It is a colourless oil giving a crystalline picrate and a styphnate with m.p. 191.5-193°C and 171-2°C respectively. The structure has been established as 1:2:3:4-tetrahydro-7-hydroxy-l-isobutyl-6- methoxy-2-methylisoquinoline. It yields a methyl ether, forming a picrate, m.p. 180-2°C and a styphnate, m.p. 210-2°C. The corresponding ethyl ether also gives a picrate and styphnate with m.p. ISO-3°C and 182-3°C respectively.
DefinitionChEBI: Lophocerine is a member of isoquinolines.
Synthesis Reference(s)The Journal of Organic Chemistry, 24, p. 1106, 1959 DOI: 10.1021/jo01090a018
ReferencesBobbitt, Chou., J. Org. Chem., 24, 1106 (1959)
1,2,3,4-Tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)isoquinolin-7-ol Preparation Products And Raw materials
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