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| (7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Basic information |
Product Name: | (7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol | Synonyms: | (7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol;Ochotensine;Spiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol, 3',4',6,8-tetrahydro-7'-methoxy-2'-methyl-6-methylene-, (7'S)- | CAS: | 4959-88-0 | MF: | C21H21NO4 | MW: | 351.4 | EINECS: | | Product Categories: | | Mol File: | 4959-88-0.mol | |
| (7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Chemical Properties |
Melting point | 252°C | Boiling point | 500.0±50.0 °C(Predicted) | density | 1.37±0.1 g/cm3(Predicted) | pka | 10.48±0.20(Predicted) |
| (7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Usage And Synthesis |
Description | This phenolic alkaloid occurs in Corydalis ochotensis and C. sibirica Pers. It is dextrorotatory with [Q:l~4 + 51.7° (CHCI3) and [o:J~3 + 63.9° (0.1 N/HCI). The
methiodide yields tetragonal crystals from MeOH with m.p. 215°C. The 0-
methyl ether is ochotensimine (q.v.). The above structure has been confirmed by
the total synthesis of the optically inactive form of the alkaloid. | Definition | ChEBI: Ochotensine is a member of isoquinolines. | References | Manske., Can. J. Res., 18B, 75 (1940) McLean, Mei-Sie Lin, McDonald, Trotter., Tetrahedron Lett., 185 (1966) McDonald, Trotter., J. Chern. Soc., B, 929 (1966) Total synthesis:
Irie, Kishimoto, Uyeo., J. Chern. Soc., C, 3051 (1968) |
| (7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Preparation Products And Raw materials |
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