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| 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Basic information |
| 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Chemical Properties |
Melting point | 210-212°C | storage temp. | 2-8°C | solubility | DMSO: ≥5mg/mL at warmed to 60°C | form | powder | color | white to beige |
Hazard Codes | Xn | Risk Statements | 22 | WGK Germany | 3 |
| 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Usage And Synthesis |
Uses | CDPPB may be used in mGluR5-mediated cell signaling studies. | Uses | 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury. | Biochem/physiol Actions | CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator. | storage | +4°C |
| 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Preparation Products And Raw materials |
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