| Company Name: |
ChemPep, Inc.
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| Tel: |
+1 (888) 615-9178 / (561) 791-8787 |
| Email: |
service@chempep.com |
| Products Intro: |
Product Name:Boc-NH-PEG10-CH2CH2COOH
Purity:95% Package:1 g, 5 g Remarks:PEGylation Reagents
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| Company Name: |
Amatek Scientific Co. Ltd.
|
| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:BocNH-PEG10-CH2CH2COOH
CAS:2410598-01-3
Purity:97% HPLC Package:5g;25g;100g;1kg
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Boc-NH-PEG10-CH2CH2COOH manufacturers
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| | Boc-NH-PEG10-CH2CH2COOH Basic information |
| Product Name: | Boc-NH-PEG10-CH2CH2COOH | | Synonyms: | Boc-NH-PEG10-CH2CH2COOH;BocNH-PEG10-COOH;BocNH-PEG10-C2-COOH;2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29,32,35-undecaoxa-5-azaoctatriacontan-38-oic acid | | CAS: | 2410598-01-3 | | MF: | C28H55NO14 | | MW: | 629.74 | | EINECS: | | | Product Categories: | | | Mol File: | 2410598-01-3.mol |  |
| | Boc-NH-PEG10-CH2CH2COOH Chemical Properties |
| Boiling point | 683.5±55.0 °C(Predicted) | | density | 1.121±0.06 g/cm3(Predicted) | | pka | 4.28±0.10(Predicted) |
| | Boc-NH-PEG10-CH2CH2COOH Usage And Synthesis |
| Biological Activity | Boc-NH-PEG10-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Boc-NH-PEG10-CH2CH2COOH Preparation Products And Raw materials |
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