| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:15(R),19(R)-hydroxy Prostaglandin F2α
CAS:1224444-23-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:15(R),19(R)-hydroxy Prostaglandin F2α
CAS:1224444-23-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:15(R),19(R)-hydroxy Prostaglandin F2α
CAS:1224444-23-8
Purity:98% Package:50μg;100μg;500μg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:15(R),19(R)-hydroxy Prostaglandin F2α
CAS:1224444-23-8
Purity:0 Package:50mg;10mg
|
|
| | 15(R),19(R)-hydroxy Prostaglandin F2α Basic information |
| | 15(R),19(R)-hydroxy Prostaglandin F2α Chemical Properties |
| Boiling point | 600.1±55.0 °C(Predicted) | | density | 1.213±0.06 g/cm3(Predicted) | | solubility | DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS (pH 7.2): 10 mg/ml | | pka | 4.76±0.10(Predicted) |
| | 15(R),19(R)-hydroxy Prostaglandin F2α Usage And Synthesis |
| Description | 19(R)-Hydroxylated prostaglandins (PGs) occur in μg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R).1 19(R)-Hydroxylated PGs are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate.2 The 15(R)-hydroxy epimer of these 19-hydroxylated PGs is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated PGs is not well established. In the F-series, 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.3 | | References | 1. Cooper, I., and Kelly, R.W. The measurement of E and 19-hydroxy E prostaglandins in human seminal plasma Prostaglandins 10(3),507-514(1975).
2. Marley, P.B., Rodger, J.C., White, I.G., et al. 19-Hydroxylated prostaglandins in the semen of the marsupial Trichosurus vulpecula (brush-tailed possum) Comp. Biochem. Physiol. B Biochem. Mol. Biol. 70(3),619-621(1981).
3. Woodward, D.F., Protzman, C.E., Krauss, A.H.P., et al. Identification of 19(R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist Prostaglandins 46(4),371-383(1993). |
| | 15(R),19(R)-hydroxy Prostaglandin F2α Preparation Products And Raw materials |
|