(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid manufacturers
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| (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Basic information |
Product Name: | (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid | Synonyms: | (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid;AMG 837;(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid (AMG-837 free acid) 1259389-38-2 (calium salt hydrate);(betaS)-beta-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid;AMG-837; AMG837;CS-1283;Benzenepropanoic acid, β-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-, (βS)- | CAS: | 865231-46-5 | MF: | C26H21F3O3 | MW: | 438.44 | EINECS: | | Product Categories: | | Mol File: | 865231-46-5.mol | |
| (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Chemical Properties |
Melting point | 139-142 °C | Boiling point | 565.8±50.0 °C(Predicted) | density | 1.251±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | form | Powder | pka | 4.20±0.10(Predicted) |
| (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Usage And Synthesis |
Uses | AMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity. |
| (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Preparation Products And Raw materials |
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