羟基脒双(甲磺酸)
| 中文名称 | 羟基脒双(甲磺酸) |
|---|---|
| 中文同义词 | 羟芪巴脒*DNA和RNA染料*;羟基脒双(甲磺酸);4-(2-(4-(氨基亚氨基)苯基)乙烯基)-3-羟基苯甲脒二甲磺酸盐;荧光金;化合物 HYDROXYSTILBAMIDINE BIS(METHANESULFONATE) |
| 英文名称 | HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe] |
| 英文同义词 | HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe];Fluoro-Gold;4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate);Hydroxystilbamidine *CAS 223769-64-0*;HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe];4-[(E)-2-(4-Carbamimidoylphenyl)ethenyl]-3-hydroxybenzene-1-carboximidamide |
| CAS号 | 223769-64-0 |
| 分子式 | C17H20N4O4S |
| 分子量 | 376.43 |
| EINECS号 | |
| 相关类别 | 荧光探针，标记，颗粒和染色 |
| Mol文件 | 223769-64-0.mol |
| 结构式 |  |
羟基脒双(甲磺酸) 性质
| 储存条件 | 2-8°C |
|---|---|
| 溶解度 | 可溶于水 |
| 形态 | 粉末状 |
| 颜色 | 浅黄至黄色 |
It is found that the trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) permits the recovery of mRNA after polysome released with Nonidet P-40 (NP-40). Sucrose gradient analysis of detergent-lysed postnuclear supernates is used to analyze the size distribution of NP-40-released polysomes. The heparin gradient shows some polyribosomes, whereas the Hydroxystilbamidine bis(methanesulfonate) gradient shows a remarkably large peak of very heavy polyribosomes. This peak is obtained reproducibly if Hydroxystilbamidine bis(methanesulfonate) is present before the addition of NP-40.
Hydroxystilbamidine bis(methanesulfonate) is an effective suppressor of the plaque-forming cell (PFC) response when given before sheep erythrocytes (SRBC) stimulation. Hydroxystilbamidine bis(methanesulfonate) depresses the plaque response of the treated mice. Fewer PFC are observed in Hydroxystilbamidine bis(methanesulfonate)-treated mice throughout the experiment, but the level of suppression decreases with time. By day 14, the number of PFC observed in both the Hydroxystilbamidine bis(methanesulfonate) treated mice and the control group is essentially at the background level.