Ripasudil Hydrochloride

Ripasudil Hydrochloride Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:Ripasudil Hydrochloride
CAS:223644-02-8
Purity:99% Package:25KG;5KG;1KG
Company Name: Suzhou Haiheng Biological Pharmaceutical Co., Ltd.  
Tel: 0512-65045967 15365387483
Email: sales@haihengpharm.com
Products Intro: Product Name:Ripasudil Hydrochloride
CAS:223644-02-8
Purity:98% Package:1gram ,10gram, 100gram
Company Name: Pharmacodia (Beijing) Co.,Ltd  
Tel: +86-400-851-9921
Email: sales@pharmacodia.com
Products Intro: Product Name:Ripasudil Hydrochloride
CAS:223644-02-8
Purity:98% HPLC Package:5mg,10mg,50mg,100mg
Company Name: Nanjing Meihao Pharmaceutical Technology Co., Ltd.  
Tel: meitaochem@126.com
Email: meitaochem@126.com
Products Intro: Product Name:Ripasudil
CAS:223644-02-8
Purity:99% HPLC Package:1g,5g,100g
Company Name: Wuhan Topule  
Tel: +86-02787215551 +86-19945035818
Email: 2936752263@qq.com
Products Intro: CAS:223644-02-8
Purity:98% HPLC Package:10mg.1g.1kg.5KG;1KG
Ripasudil Hydrochloride Basic information
Product Name:Ripasudil Hydrochloride
Synonyms:Ripasudil Hydrochloride;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride;Glanatec
CAS:223644-02-8
MF:C15H19ClFN3O2S
MW:359.8466632
EINECS:
Product Categories:
Mol File:223644-02-8.mol
Ripasudil Hydrochloride Structure
Ripasudil Hydrochloride Chemical Properties
Melting point 258-259 °C (decomp)
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
Ripasudil Hydrochloride Usage And Synthesis
UsesRipasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.
UsesRipasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension.
Ripasudil Hydrochloride Preparation Products And Raw materials
Raw materials4-Fluoro-5-isoquinolinesulfonyl chloride hydrochloride (1:1)-->(S)-1-BOC-2-METHYL-[1,4]DIAZEPANE
Tag:Ripasudil Hydrochloride(223644-02-8) Related Product Information
Ripasudil Ripasudil hydrochloride dihydrate