Company Name: |
Pharmacodia (Beijing) Co.,Ltd
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Tel: |
+86-400-851-9921 |
Email: |
sales@pharmacodia.com |
Products Intro: |
Product Name:Ripasudil Hydrochloride CAS:223644-02-8 Purity:98% HPLC Package:5mg,10mg,50mg,100mg
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Company Name: |
Wuhan Topule
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Tel: |
+86-02787215551 +86-19945035818 |
Email: |
2936752263@qq.com |
Products Intro: |
CAS:223644-02-8 Purity:98% HPLC Package:10mg.1g.1kg.5KG;1KG
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| Ripasudil Hydrochloride Basic information |
Product Name: | Ripasudil Hydrochloride | Synonyms: | Ripasudil Hydrochloride;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride;Glanatec | CAS: | 223644-02-8 | MF: | C15H19ClFN3O2S | MW: | 359.8466632 | EINECS: | | Product Categories: | | Mol File: | 223644-02-8.mol | |
| Ripasudil Hydrochloride Chemical Properties |
Melting point | 258-259 °C (decomp) | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | solubility | DMSO (Slightly), Methanol (Slightly), Water (Sparingly) | form | Solid | color | White to Off-White | Stability: | Hygroscopic |
| Ripasudil Hydrochloride Usage And Synthesis |
Uses | Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing. | Uses | Ripasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension. |
| Ripasudil Hydrochloride Preparation Products And Raw materials |
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