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1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one

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1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:PK-THPP；PKTHPP;PK THPP
CAS:1332454-07-5
Package:25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel: +86-18341751992 +86-15382112998
Email: 757984502@qq.com
Products Intro: Product Name:PK-THPP
CAS:1332454-07-5
Purity:98 Package:500mg；1g；5g；10g；25g Remarks:Provide customized services
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:PK-THPP
CAS:1332454-07-5
Purity:98% Package:$135.9/5mg;$208.9/10mg;$468.9/25mg;$872.9/50mg;$1569.9/100mg;Bulk package Remarks:98%
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:PK-THPP
CAS:1332454-07-5
Purity:>=98% (HPLC) Package:5MG Remarks:SML1326-5MG
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Products Intro: Product Name:PK-THPP
CAS:1332454-07-5
Purity:99% Package:1mg;5mg;10mg
1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one Basic information
Product Name:1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one
Synonyms:1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one;PK-THPP;1-[1-[6-[[1,1'-Biphenyl]-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]-4-piperidinyl]-1-butanone;1-Butanone, 1-[1-[6-([1,1'-biphenyl]-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]-4-piperidinyl]-;PK-THPP >=98% (HPLC);PKTHPP,PK THPP
CAS:1332454-07-5
MF:C29H32N4O2
MW:468.59
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Mol File:1332454-07-5.mol
1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one Structure
1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one Chemical Properties
storage temp. 2-8°C
solubility Soluble in DMSO
form powder
color white to beige
Safety Information
MSDS Information
1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one Usage And Synthesis
Biochem/physiol ActionsPK-THPP is a potent antagonist of tandem pore potassium channel subunit TASK-3 (KCNK9, K2P9.1) with an IC50 value of 35 nM for TASK-3 compared to 303 nM for TASK-1 and with >140 fold selectivity over a wider range of potassium channels. PK-THPP was found to act as a respiratory stimulant, stimulating breathing in isoflurane-anesthetized rats.
storageStore at +4°C
1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one Preparation Products And Raw materials
Tag:1-{1-[6-(biphenyl-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl}butan-1-one(1332454-07-5) Related Product Information