| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-MAGI2
Purity:Prestige Antibodies P Package:100μL Remarks:HPA013650
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:~1 mg/mL, affinity isolated antibody, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-ARIP, RABBIT Basic information |
| Product Name: | ANTI-ARIP, RABBIT | | Synonyms: | ANTI-S-SCAM, RABBIT;ANTI-MAGI-2 RABBIT;ANTI-ARIP, RABBIT;Anti-ARIP, Anti-S-SCAM;Anti-MAGI-2 antibody produced in rabbit;Anti-Atrophin-1-interacting protein 1;Anti-Atrophin-1-interacting protein A;Anti-MAGI-2 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-ARIP, RABBIT Structure]() |
| | ANTI-ARIP, RABBIT Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-ARIP, RABBIT Usage And Synthesis |
| Uses | Anti-MAGI2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | The gene MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2) is mapped to human chromosome 7q21 and spans 1.4 megabases. It contains 21 exons encoding a 2410 amino acid protein that contains nine potential protein-protein interaction domains. These domains include one Guk (guanylate kinase-like) domain, two WW domains and six PDZ domains. | | Biochem/physiol Actions | The gene MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2) encodes a scaffolding protein that functions in the assembly of epithelial tight junction enhancing epithelial integrity. It negatively regulates cell migration and proliferation via PTEN (phosphatase and tensin homolog), a protein involved in cell growth and apoptosis. It has been implicated in celiac disease and ulcerative colitis. |
| | ANTI-ARIP, RABBIT Preparation Products And Raw materials |
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