- THP-PEG3-OH
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- $0.00 / 100mg
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2024-10-24
- CAS:60221-37-6
- Min. Order:
- Purity:
- Supply Ability: 10g
- OH-PEG3-THP
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- $0.00 / 25g
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2024-03-25
- CAS:60221-37-6
- Min. Order: 25g
- Purity: >98.00%
- Supply Ability: 25g
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| | THP-PEG4 Basic information |
| Product Name: | THP-PEG4 | | Synonyms: | THP-PEG4;2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethanol;THP-PEG3-OH;Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]-;OH-PEG3-THP;2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol;8-(1H-tetrahydropyran-2-yloxy)-3n63-dioxaoctan-1-ol;THP-PEG3-OH/Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]- | | CAS: | 60221-37-6 | | MF: | C11H22O5 | | MW: | 234.29 | | EINECS: | | | Product Categories: | peg | | Mol File: | 60221-37-6.mol |  |
| | THP-PEG4 Chemical Properties |
| Boiling point | 270 °C | | density | 1.09±0.1 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | THP-PEG4 Usage And Synthesis |
| Description | THP-PEG4 is PEG linker containing a THP protecting group and a terminal hydroxyl. THP is an acid labile, alcohol protecting group. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG chain increases the water solubility of the compound in aqueous environments. The water solubility properties of the PEG linker are enhanced with longer PEG chains. | | Uses | THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | THP-PEG4 Preparation Products And Raw materials |
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