| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-CCR6
Purity:Prestige Antibodies P Package:100μL Remarks:HPA014488
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:clone 53103.111, purified immunoglobulin, lyophilized powder
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| Company Name: |
BD Biosciences
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| Tel: |
1 877 232 8995 U.S. orders |
| Email: |
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| Products Intro: |
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| Company Name: |
R & D Systems
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| Tel: |
612 379 2956 |
| Email: |
info@rndsystems.com |
| Products Intro: |
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| | ANTI-HUMAN CCR6 Basic information |
| | ANTI-HUMAN CCR6 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| | ANTI-HUMAN CCR6 Usage And Synthesis |
| Uses | Anti-CCR6 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. | | General Description | The gene CCR6 (C-C motif chemokine receptor 6) encodes a chemokine receptor that is mainly expressed in B cells and memory T cells. It is also found to be expressed in dendritic cells, spleen, thymus, small intestine, and peripheral blood leukocytes. The gene is mapped to human chromosome 6q27. It shares sequence similarity with G protein-coupled chemokine receptor. The acidic amino terminal contains two potential N-linked glycosylation sites, and two additional ones are located in the first and the third extracellular loops. | | Biochem/physiol Actions | The gene CCR6 (C-C motif chemokine receptor 6) encodes a chemokine receptor for the chemokine ligand CCL20, also referred to as LARC (liver and activation-regulated chemokine) or MIP-3 α (macrophage inflammatory protein-3 α). The binding of the ligand to the receptor facilitates the chemoattraction of immature dendritic cells, effector/memory T-cells and B-cells. It participates in pathology, including cancer and rheumatoid arthritis. In mucosal tissue, CCR6 participates in the regulation of humoral immunity and lymphocyte homeostasis. It also mediates dendritic cell localization. |
| | ANTI-HUMAN CCR6 Preparation Products And Raw materials |
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