186390-35-2
| 中文名称 | 186390-35-2 |
|---|---|
| 中文同义词 | 化合物 T13418 |
| 英文名称 | [1,1'-Biphenyl]-2-carboxamide, N-[1,2,3,4-tetrahydro-2-(1H-imidazol-2-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)- |
| 英文同义词 | [1,1'-Biphenyl]-2-carboxamide, N-[1,2,3,4-tetrahydro-2-(1H-imidazol-2-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-;CP-319340(free base);CP319340(free base),CP 319340(free base) |
| CAS号 | 186390-35-2 |
| 分子式 | C27H23F3N4O |
| 分子量 | 476.49 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 186390-35-2.mol |
| 结构式 |  |
186390-35-2 性质
| 沸点 | 594.3±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.342±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 13.21±0.20(Predicted) |
CP-319340 free base 是一种微粒体甘油三酯转移蛋白 (MTP) 抑制剂。
MTP
Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are necessary for lipoprotein assembly. MTP binds to ApoB with high affinity involving ionic interactions. MTP interacts at multiple sites in the N-terminal beta alpha structural domain of apoB.