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| | 5-((2,4-dimethoxynaphthalen-1-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione Basic information |
| Product Name: | 5-((2,4-dimethoxynaphthalen-1-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | | Synonyms: | 5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione;IT 901;IT901;IT-901;1584121-99-2;5-((2,4-dimethoxynaphthalen-1-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione;IT901;4,6(1H,5H)-Pyrimidinedione, 5-[(2,4-dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-;IT 901,IT901 | | CAS: | 1584121-99-2 | | MF: | C17H14N2O4S | | MW: | 342.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1584121-99-2.mol |  |
| | 5-((2,4-dimethoxynaphthalen-1-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione Chemical Properties |
| density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF:33.0(Max Conc. mg/mL);96.39(Max Conc. mM)
DMSO:33.0(Max Conc. mg/mL);96.39(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.41(Max Conc. mM) | | form | A crystalline solid | | pka | 4.68±0.20(Predicted) | | color | Orange to red |
| | 5-((2,4-dimethoxynaphthalen-1-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione Usage And Synthesis |
| Uses | IT 901 is a bioactive naphthalenethiobarbiturate derivative that potently inhibits the NF-κB subunit c-?Rel. IT 901 also revealed antitumor properties in vitro and in vivo. |
| | 5-((2,4-dimethoxynaphthalen-1-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione Preparation Products And Raw materials |
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