Company Name: |
Alabiochem Tech.Co., Ltd.
|
Tel: |
0512-58900862 400-0707518 |
Email: |
sales@alabiochem.com |
Products Intro: |
Product Name:Propargyl-PEG12-amine;Propyne-PEG12-NH2 CAS:2264091-73-6 Purity:98% Package:1g;5g;25; 100g;bulk
|
Propargyl-PEG12-amine manufacturers
- Propargyl-PEG12-amine
-
- $0.00 / 1g
-
2024-03-26
- CAS:2264091-73-6
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
|
| Propargyl-PEG12-amine Basic information |
Product Name: | Propargyl-PEG12-amine | Synonyms: | Propargyl-PEG12-amine;Propyne-PEG12-NH2;Propargyl-PEG13- Amine;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yn-1-amine | CAS: | 2264091-73-6 | MF: | C27H53NO12 | MW: | 583.71 | EINECS: | | Product Categories: | | Mol File: | 2264091-73-6.mol | ![Propargyl-PEG12-amine Structure](CAS/20210305/GIF/2264091-73-6.gif) |
| Propargyl-PEG12-amine Chemical Properties |
Boiling point | 608.1±50.0 °C(Predicted) | density | 1.084±0.06 g/cm3(Predicted) | pka | 8.74±0.10(Predicted) |
| Propargyl-PEG12-amine Usage And Synthesis |
Biological Activity | Propargyl-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Propargyl-PEG12-amine Preparation Products And Raw materials |
|