| Company Name: |
Alabiochem Tech.Co., Ltd.
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| Tel: |
0512-58900862 400-0707518 |
| Email: |
sales@alabiochem.com |
| Products Intro: |
Product Name:Propargyl-PEG12-amine;Propyne-PEG12-NH2
CAS:2264091-73-6
Purity:98% Package:1g;5g;25; 100g;bulk
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Propargyl-PEG12-amine manufacturers
- Propargyl-PEG12-amine
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- $0.00 / 1g
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2024-03-26
- CAS:2264091-73-6
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | Propargyl-PEG12-amine Basic information |
| Product Name: | Propargyl-PEG12-amine | | Synonyms: | Propargyl-PEG12-amine;Propyne-PEG12-NH2;Propargyl-PEG13- Amine;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yn-1-amine | | CAS: | 2264091-73-6 | | MF: | C27H53NO12 | | MW: | 583.71 | | EINECS: | | | Product Categories: | | | Mol File: | 2264091-73-6.mol |  |
| | Propargyl-PEG12-amine Chemical Properties |
| Boiling point | 608.1±50.0 °C(Predicted) | | density | 1.084±0.06 g/cm3(Predicted) | | pka | 8.74±0.10(Predicted) |
| | Propargyl-PEG12-amine Usage And Synthesis |
| Biological Activity | Propargyl-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Propargyl-PEG12-amine Preparation Products And Raw materials |
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