PROPARGYL-PEG6-NHS ESTER
中文名称 | PROPARGYL-PEG6-NHS ESTER |
---|---|
中文同义词 | 丙炔-六聚乙二醇-琥珀酰亚胺酯;丙炔-六聚乙二醇-NHS酯;丙炔基-五聚乙二醇-丙烯酸琥珀酰亚胺酯;2,5-二氧代吡咯烷-1-基 4,7,10,13,16,19-六氧杂二十二烷-21-炔-1-酸酯;丙炔-六聚乙二醇-活性脂 |
英文名称 | Propargyl-PEG6-NHS ester |
英文同义词 | Propargyl-P5-NHS ester;Propargyl-PEG5-CH2CH2COONHS;2,5-Dioxopyrrolidin-1-yl?4,7,10,13,16,19-hexaoxadocos-21-yn-1-oate;Propargyl-PEG6-NHS ester;Propargyl-PEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;Propargyl-PEG5-C2-CONHS ester;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester |
CAS号 | 2093153-99-0 |
分子式 | C20H31NO10 |
分子量 | 445.46 |
EINECS号 | |
相关类别 | |
Mol文件 | 2093153-99-0.mol |
结构式 |
PROPARGYL-PEG6-NHS ESTER 性质
沸点 | 530.8±60.0 °C(Predicted) |
---|---|
密度 | 1.22±0.1 g/cm3(Predicted) |
溶解度 | 溶于DMSO、DCM |
Cleavable
|
PEGs
|
Alkyl/ether
|
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.